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Scalable Aqueous Reversible Addition–Fragmentation Chain Transfer Photopolymerization-Induced Self-Assembly of Acrylamides for Direct Synthesis of Polymer Nanoparticles for Potential Drug Delivery Applications AITranslate

The University of New South Wales; The University of New South Wales; The University of New South Wales; Monash University; The University of New South Wales; The University of New South Wales
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Publisher: ACS
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Abstract AITranslate

The synthesis of polymer nanoparticles for potential drug delivery applications via photoinduced electron transfer–reversible addition–fragmentation chain transfer aqueous dispersion polymerizations employing Eosin Y/triethanol amine as catalytic system is described. A scalable synthesis procedure for the polymerization of poly(dimethyl acrylamide)-b-(poly(diaceteone-stat-dimethyl acrylamide)) is reported under visible light (λmax = 530 nm). A variety of solid contents and block lengths for the solvophilic and solvophobic blocks are investigated, expanding the compositional space of worms, jellyfish, and vesicles using flow chemistry. A simple two-step process using a coupled flow reactor setup is used without the need for intermediate purification.

KeyWords AITranslate

photoPISA PETRAFT flow reactor morphology polymer nanoparticles
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DOI:https://doi.org/10.1021/acsapm.9b00280

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Citation Information:

The synthesis of polymer nanoparticles for potential drug delivery applications via photoinduced electron transfer–reversible addition–fragmentation chain transfer aqueous dispersion polymerizations employing Eosin Y/triethanol amine as catalytic system is described. A scalable synthesis procedure for the polymerization of poly(dimethyl acrylamide)-b-(poly(diaceteone-stat-dimethyl acrylamide)) is reported under visible light (λmax = 530 nm). A variety of solid contents and block lengths for the solvophilic and solvophobic blocks are investigated, expanding the compositional space of worms, jellyfish, and vesicles using flow chemistry. A simple two-step process using a coupled flow reactor setup is used without the need for intermediate purification.

quote

GB/T 7714-2015 [1] Neomy Zaquen, Huijie Zu, Ak M.N.B.P.H.A. Kadir, et al. ACS Applied Polymer Materials, 2019(1). DOI:10.1021/acsapm.9b00280.
MLA [1] Neomy Zaquen, et al., ACS Applied Polymer Materials, no. 1, 2019, https://doi.org/10.1021/acsapm.9b00280.
APA [1] Neomy Zaquen, Huijie Zu, Ak M.N.B.P.H.A. Kadir, Tanja Junkers, Per B. Zetterlund, & Cyrille Boyer. (2019). ACS Applied Polymer Materials(1). https://doi.org/10.1021/acsapm.9b00280
IEEE [1] Neomy Zaquen, Huijie Zu, Ak M.N.B.P.H.A. Kadir, Tanja Junkers, Per B. Zetterlund, and Cyrille Boyer, ACS Applied Polymer Materials, no. 1, 2019, doi: 10.1021/acsapm.9b00280. keywords: {photoPISA;PETRAFT;flow reactor;morphology;polymer nanoparticles}