Formulation Optimization for Compound Inhibitors of WC Oxidation Dissolution by Response Surface Methodology AITranslate

1Mason R L,Gunst R F, Hess J J. Statistical design and analysis of experiments with apphcafions to engineeringand science [ M]. Hoboken: John Wiley and Sons lnc, 2003. 116-124.

2Adinarayana K,Ellaiah P, Srinivasulu B, et al. Response surface methodological approach to optimize the nutri- tional parameters for neomycin production by strepto myces marinensis under solid- state fermentation [J].Process Biochemistry,2003,38(11) :1 565-1 572.

4Bacaoui A,Dahbi A, Yaacoubi A,et al. Experimental de sign to optimize preparation of activated carbons for use in water treatment[J]. Environmental Science and Tech- nology,2002,3G(17) :3 844-3 849.

5Noordin M Y, Venkatesh V C,Sharf S,et al. Applica tion of response surface methodology in describing the performance of coated carbide tools when turning AISI 1045 steel[J]. Journal of Materials Processing and Tech- nology, 2004,145 (1) : 46-58.

6任露泉.试验设计及其优化(第二版)[M].北京:高等教育出版社,2003.265-278.

7张润楚,刘民千,杨建峰,等.回归分析与实验设计[M].北京:机械工业出版社,2010.171-176.

8汪仁官.实验设计与分析[M].北京:中国统计出版社,1998..

Basic Information:

DOI：

Chinese Library Classification Number:TF111.31[冶金工程—冶金物理化学]

Citation Information:

Based on the principle of universal central composite rotatable design （CCD）,the formulation of compound inhibitors was optimized and the related experiment was designed, by response surface analysis. Effects of compound inhibitors on oxidation dissolution of WC powder were investigated in hydrothermal environment,and compound inhibitors are composed of sodium citrate, borax, nitro-benzoic acid triethano- lamine ester （simplified as aromatic amine ester）. The electromotive force changes of different inhibitor so- lution were determined before and after adding WC powder. Response surface and contour line were drawn with AE as the response indicator. The interaction between various factors and leaching degree of WC in different solution were analyzed. The results show that with max response value i. e. minimum WC oxida- tion dissolution,the compound inhibitor formula is as follows：sodium citrate 0. 983 5 g/100 mLH20,borax 2. 507 4 g/100 mLH20,aromatic amine ester with 1 ： 1.1 molar ratio 2. 510 3 g/100 mLH20. And the pre- dictive value of the regression model is 0. 059 07 V and the actual measured value is 0. 058 36 V.