Synthesis of Fe₃O₄-Au-Ag Composite Nanomaterials and Their Application as Raman Spectrum Substrate AITranslate

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Chinese Library Classification Number:O657.61[理学—分析化学]

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Fe₃O₄ nanoparticles were prepared by triethanolamine hydrothermal method,nano Au-Ag alloy sol was synthesized by sodium citrate co-reduction method,and Fe₃O₄ nanoparticles were modified by surface amination.Subsequently,Au-Ag nanoparticles were loaded onto Fe₃O₄ to synthesize Fe₃O₄-Au-Ag magnetic composite nanomaterials,and the composite materials were characterized using XRD,UV-Vis,TEM,and EDS.The composite materials were used as a surface-enhanced Raman scattering(SERS)substrate and a new method for detecting levofloxacin was developed using a standard working curve.Spiked recovery experiments were also conducted.In addition,the mechanism of Fe₃O₄-Au-Ag enhancing Raman spectrum of levofloxacin was analyzed.There is a relatively good linear relationship between the SERS peak intensity and the logarithm of levofloxacin concentration(10^-7~10^-3mol/L).The standard working curve equation is y=957x+7516.2,and the correlation coefficient R² is 0.9522.This method has good stability with a relative standard deviation of 2.2%,and its sensitivity is relatively high with a detection limit of 2×10^-9mol/L and spiked recovery rate of over 93%.The mechanism of Fe₃O₄-Au-Ag enhancing Raman spectrum of levofloxacin includes electromagnetic enhancement mechanism,chemical enhancement mechanism,and three enhancement models(mirror model,antenna model,and lightning rod model).This new method is expected to be used in such fields as agriculture,industry,environment,food,medicine,and health,achieving highly sensitive detection of antibiotics in actual samples.