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Silica Gel Functionalized with Polyethylenimine as Advanced Sorbents for the Removal of Endotoxin from Gelatin AITranslate

Weijie Zhang; Bing Zhang; Jianing Wang; Yihu Wang; Xiaofeng Cao; Weipeng Lu; Yanchuan Guo;
University of Chinese Academy of Sciences; Technical Institute of Physics and Chemistry; Technical Institute of Physics and Chemistry; Technical Institute of Physics and Chemistry; Technical Institute of Physics and Chemistry; Technical Institute of Physics and Chemistry; University of Chinese Academy of Sciences
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Publisher: ACS
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Abstract AITranslate

Gelatin is one of the essential materials for tissue engineering for its unique physicochemical properties. The endotoxin in gelatin needs to be controlled at a reasonable level to guarantee biosafety when applied to the human body. However, the isothermal titration calorimetry results showed specific interactions between gelatin and endotoxin, suggesting the difficulties of removing endotoxin from gelatin in mild conditions. In this work, a polyethyleneimine-grafted silica gel adsorbent for endotoxin was designed and prepared. Results showed that the prepared endotoxin adsorbent could remove endotoxin from gelatin without significantly changing the structures and properties of gelatin.

KeyWords AITranslate

adsorption endotoxin gelatin sorbent polyethylenimine
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Basic Information:

DOI：https://doi.org/10.1021/acsapm.3c00055

Chinese Library Classification Number:

Citation Information:

Gelatin is one of the essential materials for tissue engineering for its unique physicochemical properties. The endotoxin in gelatin needs to be controlled at a reasonable level to guarantee biosafety when applied to the human body. However, the isothermal titration calorimetry results showed specific interactions between gelatin and endotoxin, suggesting the difficulties of removing endotoxin from gelatin in mild conditions. In this work, a polyethyleneimine-grafted silica gel adsorbent for endotoxin was designed and prepared. Results showed that the prepared endotoxin adsorbent could remove endotoxin from gelatin without significantly changing the structures and properties of gelatin.

quote

GB/T 7714-2015 [1] Weijie Zhang, Bing Zhang, Jianing Wang, et al. ACS Applied Polymer Materials, 2023(5). DOI:10.1021/acsapm.3c00055.
MLA [1] Weijie Zhang, et al., ACS Applied Polymer Materials, no. 5, 2023, https://doi.org/10.1021/acsapm.3c00055.
APA [1] Weijie Zhang, Bing Zhang, Jianing Wang, Yihu Wang, Xiaofeng Cao, Weipeng Lu, & Yanchuan Guo. (2023). ACS Applied Polymer Materials(5). https://doi.org/10.1021/acsapm.3c00055
IEEE [1] Weijie Zhang, Bing Zhang, Jianing Wang, Yihu Wang, Xiaofeng Cao, Weipeng Lu, and Yanchuan Guo, ACS Applied Polymer Materials, no. 5, 2023, doi: 10.1021/acsapm.3c00055. keywords: {adsorption;endotoxin;gelatin;sorbent;polyethylenimine}